Prof Philip Bayly, Mechanical Engineering & Materials Science, Washington University, USA

The Brain in Motion: Visualizing Brain Biomechanics and Understanding Traumatic Brain Injury
When Jan 20, 2020
from 02:00 PM to 03:00 PM
Where LR1
Contact Name
Contact Phone 01865 273651
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High linear and angular accelerations of the skull can lead to rapid deformation of brain tissue and subsequent traumatic brain injury (TBI), but the precise mechanisms remain incompletely understood. Computer simulations of head-brain biomechanics offer enormous potential for improved understanding and prevention of TBI. However simulations must be complemented by biomechanical measurements to parameterize and validate the underlying mathematical models. The nonlinear, anisotropic, viscoelastic, heterogeneous character of brain tissue, and the intricate connections between the brain and skull all play important roles in the brain’s response to skull acceleration. Studies of animal brains and ex vivo brain tissue have led to useful advances, but these models provide only limited insight into the response of the intact human brain.  On the other hand, efforts to understand the motion of the human brain in vivo are complicated by the fact that it is delicate, hidden, and well-protected by the skull. I will describe MR imaging techniques to characterize brain deformation, estimate brain material properties, and illuminate the boundary conditions between brain and skull, with the objective of improving the ability to simulate TBI.

Short Biography

Philip V. (Phil) Bayly is The Lilyan and E. Lisle Hughes Professor of Mechanical Engineering and Chair of the Department of Mechanical Engineering and Materials Science at Washington University in St. Louis. Dr. Bayly earned an A.B. in Engineering Science from Dartmouth College, an M.S. in Engineering from Brown University, and a Ph.D. in Mechanical Engineering from Duke University. Before pursuing his doctorate, he worked as research engineer for the Shriners Hospitals and as a design engineer for Pitney Bowes.

Dr. Bayly has been a member of the faculty at Washington University since 1993, and Chair since 2008. His research involves the study of nonlinear dynamic phenomena in mechanical and biological systems. He is particularly interested in the use of imaging technology and image processing to understanding the mechanics and material properties of biological tissues and cells.  His research has been funded by the National Science Foundation, the Whitaker Foundation, and the National Institutes of Health.